Kāore he rongoā mō te mate a Alzheimer, engari kei te rapu tonu ngā kaipūtaiao i ngā huarahi hei rongoā i ngā tohu o te mate.
Kei te mahi hoki ngā kairangahau ki te kimi wawe i te mate wareware e pā ana ki te mate a Alzheimer, nā te mea ka taea e te kimi wawe te āwhina i te maimoatanga.
E ai ki tētahi rangahau hou i whakaputaina i roto i te Frontiers in Aging Neuroscience, ko te waikawa formic i roto i te mimi he tohu pea mō te tautuhi wawe i te mate a Alzheimer.
E whakaahua ana te US Centers for Disease Control and Prevention (CDC) i te mate wareware hei "ngā ngoikoretanga o te mahara, te whakaaro, te whakatau kaupapa rānei e whakararuraru ana i ngā mahi o ia rā."
Haunga te mate a Alzheimer, kei reira anō ētahi atu momo mate wareware pērā i te mate wareware me ngā tinana Lewy me te mate wareware vascular. Engari ko te mate a Alzheimer te momo mate wareware tino noa.
E ai ki te pūrongo a te Alzheimer's Disease Association mō te tau 2022, tata ki te 6.5 miriona tāngata i te United States e noho ana me te mate. Hei tāpiri, e matapaetia ana e ngā kairangahau ka piki rua taua tau i te tau 2050.
Hei tāpiritanga, ko te hunga kua pāngia e te mate a Alzheimer kua pāngia e te uaua ki te horomi, ki te kōrero, me te hikoi.
Tae noa ki ngā tau tōmua o te tekau tau atu i 2000, ko te tātaritanga tupapaku anake te huarahi hei whakaū mēnā he mate a Alzheimer, he momo mate wareware rānei tō te tangata.
E ai ki te National Institute on Aging, ka taea e ngā tākuta te mahi i te lumbar puncture, e mōhiotia ana ko te lumbar puncture, hei tirotiro i ngā tohu koiora e pā ana ki te mate a Alzheimer.
Ka rapu ngā tākuta i ngā tohu koiora pēnei i te beta-amyloid 42, te wāhanga matua o ngā papa amyloid i roto i te roro, ā, ka rapu pea i ngā āhuatanga rerekē i runga i te matawai PET.
"Mā ngā tikanga whakaahua hou, inā koa ko te whakaahua amyloid, te whakaahua amyloid PET, me te whakaahua tau PET, ka taea e tātou te kite i ngā āhuatanga rerekē o te roro i te wā e ora ana te tangata," te kī a te ahorangi hauora me te rata o Te Whare Wānanga o Michigan, a Kenneth M. Dr. Langa. i Ann Arbor, kāore i uru ki te rangahau, i kōrero mō tētahi podcast Michigan Medicine tata nei.
Ka taea e ētahi kōwhiringa maimoatanga te whakaiti i te kaha o ngā tohumate huango me te whakaroa i te haere whakamua o te mate, ahakoa kāore e taea te whakaora.
Hei tauira, ka tohua pea e te tākuta he rongoā pēnei i te donepezil, te galantamine rānei hei whakaiti i ngā tohumate o te mate huango. Tērā pea ka whakaroahia te haere whakamua o te mate a Alzheimer e tētahi rongoā rangahau e kīia nei ko te lecanemab.
Nā te mea he nui te utu mō te whakamātautau mō te mate a Alzheimer, ā, kāore pea e taea e te katoa te whiwhi, kei te whakatairanga ētahi kairangahau i te tirotiro wawe.
I tātarihia ngātahitia e ngā kairangahau o Te Whare Wānanga o Shanghai Jiaotong me te WuXi Institute of Diagnostic Innovation o Haina te tūranga o te waikawa formic hei tohu koiora mō te mate a Alzheimer i roto i te mimi.
I whiriwhiria e ngā kaipūtaiao tēnei matū motuhake i runga i ngā rangahau o mua mō ngā tohu koiora o te mate a Alzheimer. E kī ana rātou ko te pākia o te formaldehyde he āhuatanga matua o te ngoikore o te hinengaro e pā ana ki te koroheketanga.
Mō tēnei rangahau, i tohua e ngā kaituhi he 574 ngā kaiuru mai i te Whare Hauora Mahara o te Hōhipera Tangata Tuaono o Shanghai, Haina.
I wehea e rātou ngā kaiuru ki ngā rōpū e rima i runga i tā rātou mahi i ngā whakamātautau mahi hinengaro; i ahu mai ēnei rōpū i te hinengaro hauora ki te mate a Alzheimer:
I kohia e ngā kairangahau ngā tauira mimi mai i ngā kaiuru mō ngā taumata waikawa formic me ngā tauira toto mō te tātaritanga DNA.
Mā te whakatairite i ngā taumata waikawa formic i roto i ia rōpū, i kitea e ngā kairangahau ngā rerekētanga i waenga i ngā kaiuru hauora hinengaro me te hunga he iti nei te ngoikore o te hinengaro.
I roto i ngā rōpū he iti iho te kaha o te hinengaro, he teitei ake te taumata o te waikawa formic i roto i te mimi i ērā o ngā rōpū he hauora ō rātou mahi hinengaro.
Hei tāpiri, he nui ake ngā taumata waikawa formic i roto i te mimi o ngā kaiuru whai mate a Alzheimer i ngā kaiuru hauora hinengaro.
I kitea hoki e ngā kaipūtaiao he hononga kino i waenga i te taumata o te waikawa formic i roto i te mimi me ngā whakamātautau hinengaro i ngā wāhanga o te mahara me te aro.
"I tino piki ake te UA i roto i te rōpū tātaritanga [te hekenga hinengaro whaiaro], ko te tikanga ka taea te whakamahi i te UA hei tātaritanga wawe [o te mate a Alzheimer]," te tuhituhi a ngā kaituhi.
He mea nui ngā hua o tēnei rangahau mō ētahi take, tae atu ki te utu nui o te tautuhi i te mate a Alzheimer.
Mena ka whakaatuhia e ngā rangahau anō ka taea e te mimi te kite i te hekenga o te hinengaro, ka taea tēnei te whakamahi hei whakamātautau ngāwari ki te whakamahi, ā, he utu tika hoki.
Hei tāpiritanga, mēnā ka taea e taua whakamātautau te kite i te hekenga o te hinengaro e pā ana ki te mate a Alzheimer, ka taea e ngā tohunga hauora te wawao wawe atu.
I kōrero a Tākuta Sandra Petersen, DNP, te tumuaki tuarua o te hauora me te oranga tinana i Pegasus Senior Living, ki a Medical News Today mō te rangahau:
"Ka tīmata ngā panonitanga o te mate a Alzheimer i te 20 ki te 30 tau i mua i te tautuhi mate, ā, he maha ngā wā kāore e kitea kia puta rā anō he kino nui. E mōhio ana mātou mā te kitenga wawe ka nui ake ngā kōwhiringa maimoatanga mō ngā tūroro me te kaha ki te whakamahere mō te tiaki ā muri ake nei."
"Mēnā ka puta he putanga hou i roto i tētahi whakamātautau pēnei (kāore e pokanoa, he iti hoki te utu) e wātea ana ki te marea whānui, ka tino huri te ao i roto i te pakanga ki te mate a Alzheimer," te kī a Tākuta Peterson.
Nō nā tata nei i kitea e ngā kaipūtaiao tētahi tohu koiora hei āwhina i ngā tākuta ki te tautuhi wawe i te mate a Alzheimer. Mā tēnei ka taea e ngā tākuta…
Ko ngā kitenga hou i roto i ngā kiore ka āwhina pea i tētahi rā ki te waihanga i tētahi whakamātautau toto ka waiho hei wāhanga o te tirotiro auau mō te mate a Alzheimer me ētahi atu momo…
E whakamahi ana tētahi rangahau hou i ngā matawai roro PET hei matapae i te hekenga o te hinengaro i runga i te aroaro o ngā pūmua amyloid me te tau i roto i te roro, me ētahi atu…
Kei te whakamahi ngā tākuta i ngā momo whakamātautau hinengaro me ngā matawai hei tautuhi i te mate a Alzheimer. Kua whakawhanakehia e ngā kairangahau tētahi pūnaha ka taea te whakamahi ki tētahi…
Tērā pea ka kitea ngā tohu o te mate wareware mā te tirotiro tere i ngā kanohi i tētahi rā.